Jun 19, 2026
Ibogaine is regularly categorized as a psychedelic — but that label may be misleading in ways that matter. In this micro, James offers a crash course in what ibogaine actually is: where it comes from, how its unusual pharmacology works, what it does to the mind, and why it holds a position in addiction medicine that no other drug on earth can claim. The risk profile is part of the picture too.
This is a clip from 'Psychedelics in Research & Practice | James W. Jesso', Adventures Through The Mind Podcast, episode 200
FULL EPISODE
MORE IBOGAINE EPISODES
- Treating Traumatic Brain Injury with Ibogaine | Dr. Nolan Williams ~ ATTMind 188
- Ibogaine Medical Subculture | Jonathan Dickinson ~ ATTMind 003
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EPISODE BREAKDOWN AND TIMESTAMPS
- (00:00) — What is ibogaine?
- (00:43) — An oneirogen, not a psychedelic
- (01:33) — Closed-eye visuals and the life review
- (02:02) — Pharmacological complexity: the "14th century key" metaphor
- (04:39) — Duration and physical challenges of the experience
- (06:34) — Cardiac risk: the only psychedelic that can directly cause death
- (09:01) — Encountering ancestors and the Bwiti tradition
- (09:51) — A brief history: from West Africa to underground use
- (10:58) — Stopping opioid addiction in a single session
- (12:21) — The current treatment landscape
- (14:44) — Reversing traumatic brain injury: the Stanford research
- (18:47) — Brain de-aging and multiple sclerosis potential
- (19:53) — Outro